Research Authors

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 139 Reviews
8.2
Supplement Facts
Serving Size:  4 capsules
Amount Per Serving
%DV
Chloride (from glucosamine hydrochloride potassium sulfate)
170 mg 
7%
Sodium (from chondroitin sulfate sodium)
120 mg
5%
Potassium (from glucosamine hydrochloride potassium sulfate)
190 mg 
4%
GlucosamineHydrochloride Potassium Sulfate
1500 mg
Chondroitin sulfate Sodium
1200 mg
MSM (Methylsulfonylmethane)(OptiMSM®)
1000 mg

Top Medical Research Studies

We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.

Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.
Read More

Most Useful Reviews

9
Reduces joint pain
197 people found this helpful
An excellent complex for joints at a fantastic price, particularly compared to pharmacies. Within a week of use, I noticed that my joints stopped crunching, and after a month, the pain significantly decreased. I will definitely order more!
Read More
9
Effective without side effects
119 people found this helpful
I am absolutely delighted with the effect of this drug! Suffering from psoriatic arthritis, I endured immense pain in my hands. After taking harmful synthetic drugs for 1.5 years with side effects, I sought alternative treatments. A nutritionist suggested this drug, and I found that it works wonders without any side effects. It has brought me relief from my symptoms, which I'm very thankful for!
Read More
9
Knees improved
107 people found this helpful
I ordered this supplement for my grandmother. She reported feeling happy with it as her knees stopped hurting.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
  • All Researches
We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.

Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.
Read More

User Reviews

USERS' SCORE
Good
Based on 139 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Reduces joint pain
197 people found this helpful
An excellent complex for joints at a fantastic price, particularly compared to pharmacies. Within a week of use, I noticed that my joints stopped crunching, and after a month, the pain significantly decreased. I will definitely order more!
Read More
9
Effective without side effects
119 people found this helpful
I am absolutely delighted with the effect of this drug! Suffering from psoriatic arthritis, I endured immense pain in my hands. After taking harmful synthetic drugs for 1.5 years with side effects, I sought alternative treatments. A nutritionist suggested this drug, and I found that it works wonders without any side effects. It has brought me relief from my symptoms, which I'm very thankful for!
Read More
9
Knees improved
107 people found this helpful
I ordered this supplement for my grandmother. She reported feeling happy with it as her knees stopped hurting.
Read More
9
Cartilage restoration
64 people found this helpful
A good product! I have long suffered from a sore neck and back due to my sedentary office work and lifestyle. Initially, I didn't seek medical advice, but eventually, I had an MRI that revealed arthritis. The doctor assured me that gymnastics and chondroprotectors could help ease the pain and improve my quality of life. After about a year of exercise, I found some relief but was still in discomfort. I ordered from iHerb, knowing it offers a good selection at reasonable prices. Chondroprotectors help restore cartilage tissue, although the benefits take time, becoming apparent after several weeks. My doctor indicated I may need to take them long-term as they don't affect the stomach or liver. They provide me with relief after about two weeks, and I highly recommend them!
Read More
9
Knee pain relief
11 people found this helpful
Super remedy! I use it for my husband's koksartroz, and the pain in his knee has ceased. We consistently order this product.
Read More

Frequently Asked Questions

9
Stops joint pain
11 people found this helpful
My husband benefited from this product. After two weeks of taking the capsules, his joints stopped hurting, benefiting from my recommendation. I have now started my mother on it. This package offers excellent value for price and quantity. The combination of Chondroitin, Glucosamine, and MSM is recommended for at least three months. I appreciate IHERB's fast delivery; the order arrived within just five days.
7.5
Joint pain relief
8 people found this helpful
I ordered this supplement for my mother, as she was experiencing hip joint pain. After about two weeks of use, she reported that her joints stopped crunching and the pain significantly reduced. I will be ordering more since the treatment requires two bottles. The capsules are easy to swallow, and I have faith in the Doctor's Best brand for dietary supplements.
9
Rapid results
7 people found this helpful
I purchased this for my husband due to ongoing knee problems. I switched from Japanese products to this glucosamine and chondroitin. Incredibly, the results were apparent within a week; his knee swelling and pain vanished. His job as a mechanic demands he is on his feet constantly, and he now feels much better. I highly recommend it!
9
Reduces joint pain
197 people found this helpful
An excellent complex for joints at a fantastic price, particularly compared to pharmacies. Within a week of use, I noticed that my joints stopped crunching, and after a month, the pain significantly decreased. I will definitely order more!
9
Pain relief achieved
6 people found this helpful
My relationship with the iHerb website began with this chondroprotector, which is effective for joint problems. After taking it for two weeks, my long-standing back and knee pain disappeared, despite carrying my large baby. I'm delighted with the results and will definitely recommend it.
9
Pain relief success
7 people found this helpful
I’m now on my second order of this remarkable remedy for joint pain. I bought it for my husband, who had chronic joint pain lasting over a year, and after just one course, his pain greatly diminished. I also suffer from chronic osteochondrosis, and after taking it for three months, I noticed significant improvement with no discomfort. My mother, at 70, is eager to try it for her shoulder and back pain. I've concluded it's wise to take this twice a year.
10
Knee pain gone
4 people found this helpful
I am 78 years old and started experiencing severe pain in my left knee nine months ago, which confined me to using Voltaren tablets. As I can't take pain medication for extended periods, I switched to Glucosamine Sulfate with Chondroitin tablets. After four months, I saw slight pain reduction but no further improvement. I then tried Glucosamine+Chondroitin with MSM and noticed a significant change after three months; my knee pain completely vanished. I can now walk without fear of sudden sharp pain! I continue taking these pills to maintain my knee health. I am immensely grateful for this help.
9
Effective without side effects
119 people found this helpful
I am absolutely delighted with the effect of this drug! Suffering from psoriatic arthritis, I endured immense pain in my hands. After taking harmful synthetic drugs for 1.5 years with side effects, I sought alternative treatments. A nutritionist suggested this drug, and I found that it works wonders without any side effects. It has brought me relief from my symptoms, which I'm very thankful for!
9
Sustained effect
5 people found this helpful
My mother endured degenerative disc disease for years, but after two months on this complex, she no longer experiences pain. I’m thrilled with the cost-effectiveness and quality of the product.
9
Effective for pain
8 people found this helpful
It is the best supplement for joints I have ever used! I experienced knee pain since I was 25. After using it according to the guidelines for half a year, I felt no discomfort for a year following treatment. I will continue to order it repeatedly because it truly works.
9
Cartilage restoration
64 people found this helpful
A good product! I have long suffered from a sore neck and back due to my sedentary office work and lifestyle. Initially, I didn't seek medical advice, but eventually, I had an MRI that revealed arthritis. The doctor assured me that gymnastics and chondroprotectors could help ease the pain and improve my quality of life. After about a year of exercise, I found some relief but was still in discomfort. I ordered from iHerb, knowing it offers a good selection at reasonable prices. Chondroprotectors help restore cartilage tissue, although the benefits take time, becoming apparent after several weeks. My doctor indicated I may need to take them long-term as they don't affect the stomach or liver. They provide me with relief after about two weeks, and I highly recommend them!
7.5
Reduced stiffness
5 people found this helpful
At 47, I began experiencing stiffness in my finger joints. By 48, my elbow joints also felt tight upon waking. I started taking glucosamine chondroitin with MSM last April and have noticed significant improvement. I no longer wake with stiffness or knee pain. I plan to continue as I've found the benefits greatly help with my autoimmune disorder symptoms.
9
Knees improved
107 people found this helpful
I ordered this supplement for my grandmother. She reported feeling happy with it as her knees stopped hurting.
9
Remarkable recovery
5 people found this helpful
I was sceptical that this would help with my serious issues of spondylarthrosis and arthrosis. After failing with prescribed treatments, I stumbled upon this supplement and, out of desperation, decided to try it. Remarkably, after just a month, I noticed a substantial decrease in pain and improvement in my general health, even enjoying a wine without hangover. I plan to order for my father as well.
We analyzed data from 35 patients with KCNA2 IgG autoantibodies linked to various neuropsychiatric issues, including cognitive impairment and seizures. These autoantibodies were notably present in cerebrospinal fluid in some patients and showed different subclasses in serum.

Notably, four patients saw significant improvement with early immunotherapy, particularly those with autoimmune encephalitis. The findings suggest that KCNA2 autoimmunity is varied, indicating the need for more research to clarify its role and therapeutic approaches.

References

  1. Arlt FA, Miske R, Machule ML, Broegger Christensen P, Mindorf S, et al. KCNA2 IgG autoimmunity in neuropsychiatric diseases. Brain Behav Immun. 2024;117:399. 10.1016/j.bbi.2024.01.220
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